СШАProduction Chemist, CGMP Manufacturing
5 дн. назад
35–40 USD / часСШАJuniorOnsite
cgmphplclyophilizationpeptide synthesis
Perform hands-on cGMP peptide manufacturing supporting upstream or downstream operations in a health and wellness company.
Обязанности
- The Production Chemist performs hands-on cGMP peptide manufacturing, supporting either upstream operations (synthesis and cleavage) or downstream operations (preparative HPLC purification and lyophilization). You will carry out assigned batch tasks safely, accurately, and on schedule. Note that cross-training in the other area may follow once you are established in the role. Experience in both areas is not required; strength in either one is enough.
- This role reports to the Supervisor, CGMP Manufacturing. Recent graduates are encouraged to apply; training will be provided.
- This role is based in Menlo Park, CA at our H&H Peptides facility.
Требования
- Bachelor’s degree in chemistry, Biochemistry, Chemical Engineering, or a related discipline (recent graduates welcome)
- Hands-on laboratory experience, through coursework, internships, or work
- Strong attention to detail and the ability to follow procedures precisely and document accurately
- Strong communication and time management skills, and ability to work independently and as part of a fast-moving team
- Ability to stand for extended periods, lift up-to 40 lbs., and wear required PPE
- Ability to work Saturdays and/or Sundays as required by the production schedule
Будет плюсом
- Background or hands-on experience in peptide synthesis (SPPS), from academic research, an internship, or industry (upstream)
- Experience with HPLC purification or lyophilization (downstream). Experience in either area is sufficient
- Familiarity with analytical HPLC and mass spectrometry for in-process data review
- Prior exposure to cGMP or regulated environments
Условия
- Competitive salary & comprehensive health benefits including medical, dental & vision
- Conditions of Employment:
- This position will require working with Hazardous Drugs (HD) and would require that Personal Protective Equipment (PPE) be worn for the length of working with these drugs. These items would include gloves, respiratory protection, gown and other items as required.
- This position requires medical approval to wear respiratory protection in the form of negative or positive pressure respirators, including N95, full face respirator, SCBA, or Powered Air Purifying Respirator (PAPR).
- Physical exertion required. Including, but not limited to, walking up to 50% of the time, standing up to 100% of the time, squatting and bending up to 20% of the time and lifting up to 80% of the time for up to a twelve hour shift. Must be able to lift up to 50lbs.
- Due to the risk of reproductive capability in handling or compounding certain Hazardous Drugs (HD) associates must be willing to confirm that they understand the potential risks (teratogenicity, carcinogenicity and reproductive effects) of handling hazardous drugs.
- We are committed to building a workforce that reflects diverse perspectives and prioritizes ethics, wellness, and a strong sense of belonging. If you're excited about this role, we encourage you to apply—even if you're not sure if your background or experience is a perfect match.
- Hims considers all qualified applicants for employment, including applicants with arrest or conviction records, in accordance with the San Francisco Fair Chance Ordinance, the Los Angeles County Fair Chance Ordinance, the California Fair Chance Act, and any similar state or local fair chance laws.
- It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
- To learn more about how we collect, use, retain, and disclose Personal Information, please visit our Global Candidate Privacy Statement .
Другое
- Hims & Hers is the leading health and wellness platform, on a mission to help the world feel great through the power of better health. We are redefining healthcare by putting the customer first and delivering access to care that is affordable, accessible, and personal, from diagnosis to treatment to delivery. No two people are the same, so we provide access to personalized care designed for results. By normalizing health & wellness challenges and innovating on their solutions, we’re making better health outcomes easier to achieve.
- Hims & Hers is a public company, traded on the NYSE under the ticker symbol “HIMS.” To learn more about the brand and offerings, you can visit and. For information on the company’s outstanding benefits, culture, and its talent-first flexible/remote work approach, see below and visit.
- Execute assigned manufacturing tasks per approved batch records, SOPs, and work instructions with minimal supervision, in a timely and efficient manner.
- Read work orders and batch records thoroughly and understand the instructions and final product specifications before starting each task.
- Upstream: perform SPPS and cleavage operations, including resin preparation, synthesizer operation, cleavage, precipitation, and crude peptide isolation.
- Upstream: verify protected amino acids batch by batch against specification, including solubility and appearance, before use.
- Downstream: perform prep HPLC purification, fraction pooling, concentration, lyophilization, and final packaging.
- Downstream: check analytical HPLC and mass of dissolved crude peptide and identify the target peptide peak by integration and mass spectrometry to guide purification and fraction pooling.
- Handle raw materials, solvents, and reagents safely; operate and clean production equipment and instruments (such as HPLCs, centrifuges, freeze dryers, stir plates, laboratory balances, mass spectrometers (optional), sonicators, vacuum ovens, and nitrogen supply) and report issues promptly.
- Prepare and label chemical solutions and buffers according to standard formulas.
- Perform in-process checks and escalate unexpected results right away.
- Complete assigned tasks on time to support batch and campaign schedules.
- Communicate delays or material and equipment constraints to the Supervisor early and support shift hand-offs.
- Complete batch records, logbooks, and standardized forms accurately and in real time, including purification and other process records.
- Review data for accuracy and completeness before submission and perform data analysis as assigned.
- Report deviations promptly, keep the work area clean, organized, and inspection-ready, and complete GMP and safety training on time.
- Work closely with teammates, Quality, QC, and Maintenance, and take part in cross-training.
- Contribute observations and data that support process improvement and product quality.
- To perform the job successfully, an individual should demonstrate the following competencies:
- Problem Solving - Identifies and resolves problems in a timely manner; Gathers and analyzes information skillfully; Develops alternative solutions; Works well in group problem solving situations.
- Teamwork - Balances team and individual responsibilities; Exhibits objectivity and openness to others' views; Gives and welcomes feedback; Supports everyone's efforts to succeed.
- Organizational Support - Follows policies and procedures; Completes tasks correctly and on time; Supports organization goals and values.
- Motivation - Sets and achieves challenging goals; Demonstrates persistence and overcomes obstacles; Measures self against standard of excellence.
- Adaptability - Adapts to changes in the work environment; Manages competing demands; Changes approach or method to best fit the situation; Able to deal with frequent change, delays, or unexpected events.